HiActi™ Recombinant Mouse IL-34 Protein, His Tag _ 90297ESInterleukin 34 (IL 34) is a cytokine with a molecular weight of 23. 98 kDa, consisting of 216 amino acid residues. IL 34 is a ligand for the colony stimulating factor 1 receptor (CSF 1R) and is primarily secreted by the adrenal glands, frontal lobe, and cortex. It plays a crucial role in the proliferation, survival, differentiation, and migration of myeloid cells. These functions are mediated by IL 34 activating the ERK1 2, JAK, and PI3K AKT signaling

89% with human and porcine

This product has broad protease inhibitory activity but does not have phosphatase inhibitory activity

featuring enzymatic cleavage sites that are as specific as those found in naturally extracted enterokinase

Once there is any residue

Small-inducible cytokine B13

42 kDa → Glycosylation shifts to 100-140 kDa (SDS-PAGE)

Experimental Protocol

It containsGln22-Asp117(CD3E)&Gln23-Thr113(CD3G)

Much IL-3 activity is dependent on co-stimulation with other cytokines

[Accession | P22413]

The product should be stored at -85~-65℃ for 1 year

Binding of FGF-21 to Klotho beta facilitates FGF R activation and autophosphorylation resulting in the initiation of multiple downstream signaling cascades