CHIR-99021 _ 53003ESCHIR 99021 is an amino pyrimidine derivative and a potent inhibitor of GSK 3 (IC50: 10 nM) and GSK 3 (IC50: 6. 7 nM). CHIR 99021 has over 500 times selectivity for GSK 3 compared to the closest homologs CDC2, ERK2, and other protein kinases. CHIR 99021 activates the Wnt catenin signaling pathway and induces cardiomyocyte differentiation of embryonic stem cells. Features Purity98% Standardized production, using factory mass production mode

The ED50 as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0

In the first round

Thrombopoietin

And it migrates as 20-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation

mycoplasma infection must be removed

Note：Be sure to mix well before use

The protein has a predicted MW of 16 kDa

we have also launched a transfection reagent specifically for suspension cells (Cat No

A: This product undergoes in vitro imaging

This product should be stored at -25~-15℃ for 2 years

The amount of enzyme required to cut >85% of the 3 μg substrate in a 1×rTEV Buffer (50 mM Tris

this product cannot catalyze the ligations between DNA and RNA or between RNA molecules